Recent Publications by members of InHANSE
Patterns of care in de-novo oligo-metastatic and oligo-recurrent head and neck cancers: A Head and Neck Cancer International Group (HNCIG) Survey
Swain M, Ghosh-Laskar S, McDowell L, Henson C, Bonomo P, Kannan S, Malouff T, Homma A, Rühle A, Lee A, Caparrotti F, Bates J, Johansen J, Thariat J, Ferrari M, Mayo-Yáñez M, Yom SS, Mehanna H, Szturz P., Nov 1 2025, In: Oral Oncology; 170:107647
Accuracy and Prognosis of Extranodal Extension on Radiologic Imaging in Human Papillomavirus-Mediated Oropharyngeal Cancer: A Head and Neck Cancer International Group (HNCIG) Real-world Study
Mehanna H, Abou-Foul AK, Henson C, Kristunas C, Nankivell PC, McDowell L, Leemans CR, van den Brekel MWM, von Buchwald C, Jakobsen KK, Grønhøj C, Rasmussen JH, Lydiatt WM, Gupta V, Branstetter BF, Klussmann JP, Wollenberg B, Schmidl B, Broglie MA, Hendrickx JJ, Awad DR, Prestwich R, Gaultier AL, Oliva M, Nair S, Noor A, Krishnan S, Iyizoba-Ebozue Z, Sethi M, Nauta IH, Zhao D, Yom SS., Oct 1 2025, In: Int J Radiat Oncol Biol Phys; 123(2):432-441. doi: 10.1016/j.ijrobp.2025.04.003.
Derivation and validation of the AJCC9V pathological stage classification for HPV-positive oropharyngeal carcinoma: a multicentre registry analysis
Ho AS, Huang SH, O'Sullivan B, Luu M, Evans M, Ferris RL, Lewis JS Jr, Seethala RR, Yom SS, Mehanna H, Branstetter BF, Saba NF, Patel SG, Lydiatt WM, Zumsteg ZS., Aug 2025, In: Lancet Oncol; 26(8):1113-1122. doi: 10.1016/S1470-2045(25)00281-5. Sep 2025, In: Erratum in: Lancet Oncol; 26(9):e465. doi: 10.1016/S1470-2045(25)00477-2.
Diagnostic Performance of Ultrasound vs Ultrasound-Guided FNAC in Thyroid Nodules: Data From the ElaTION Trial
Mehanna H, Nankivell P, Boelaert K, Woolley R, Sharma N, Sidhu PS, Madani G, Forno PD, Moreman C, Palmer A, Fulton-Lieuw T, Taylor J, Rajaguru K, Bekker J, Vaidhyanath R, Rehman T, Deeks J. Jul 2025, In: Journal of Clinical Endocrinology & Metabolism; 110(7):1997-2006. doi: 10.1210/clinem/dgae682.
Oral human papillomavirus (HPV) prevalence and genotyping among healthy adult populations in the United States and Europe: results from the PROGRESS (PRevalence of Oral hpv infection, a Global aSSessment) study
Alemany L, Felsher M, Giuliano AR, Waterboer T, Mirghani H, Mehanna H, Roberts C, Chen YT, Lara N, Lynam M, Torres M, Pedrós M, Sanchez E, Spitzer J, Sirak B, Quirós B, Carretero G, Paytubi S, Morais E, Pavón MA. Jul 2025, In: EClinicalMedicine; 9;85:103335. doi: 10.1016/j.eclinm.2025.103335. Jan 2025, Erratum for: EClinicalMedicine; 15;79:103018. doi: 10.1016/j.eclinm.2024.103018.
Development, Validation, and Valuation of a Head and Neck Cancer-Specific Health Utility Instrument (HNC-8D): A Head and Neck Cancer International Group Collaborative Study
de Almeida JR, Su J, AlShenaiber A, Noroozi H, Buttner M, Goldstein DP, Hansen A, Kowalski LP, Licitra L, Mehanna H, Noel CW, Parmar A, Porceddu S, Ringash J, Rogers S, Dos Santos MA, Simon C, Truong MT, Xu W. Jun 1 2025, In: JAMA Otolaryngol Head Neck Surg; 151(6):549-557. doi: 10.1001/jamaoto.2025.0160.
Development and validation of an artificial intelligence-based pipeline for predicting oral epithelial dysplasia malignant transformation
Shephard AJ, Mahmood H, Raza SE, Araújo AL, Santos-Silva AR, Lopes MA, Vargas PA, McCombe KD, Craig SG, James J, Brooks J, Nankivell P, Mehanna H, Khurram SA, Rajpoot NM. May 2025, In: Communications Medicine; 5(1):186. doi: 10.1038/s43856-025-00873-z.
Trends in Investigations for Suspected Head and Neck Carcinoma of the Unknown Primary: A HNCIG and IFHNOS International Survey of Practice
Williamson A, Nankivell P, Abou‐Foul AK, Ahmed M, Mehanna H. May 2025, In: Head Neck; 47(5):1478-86. https://doi.org/10.1002/hed.28065.
Challenges and Opportunities in Head and Neck Cancer Research in Developing Countries: Insights from a Fireside Chat
Chaves ALF, Kowalski LP, Marta GN, Santos-Silva AR, Vieira Muniz L, Mak MP, Gossling G, Guimaraes VS, Oliveira de Castro Junior D, de Oliveira TB, Lima CSP, Traldi Macedo L, Jacinto AA, Harada G, Barbosa MVDR, Santos IC, Batalha Filho ES, De Castro Junior G, de Marchi PRM, Matos LL, Curado MP, Mehanna H, William WN Jr. May 2025, In: JCO Glob Oncol; 11:e2500207. doi: 10.1200/GO-25-00207.
Exploring the effect of differing centre hydration and anti-emetic policies on acute gastrointestinal and renal toxicities in the De-ESCALaTE trial
Kong A, Hazell M, Iqbal G, Dunn J, Mehanna H. Apr 23 2025, In: BJC Rep; 3(1):25. doi: 10.1038/s44276-025-00132-7.
Efficacy of oral rinse and other detection methods in detecting oral human papillomavirus infections: the Oromouth cohort study
Mehanna, H., Nankivell, P., Abou-Foul, A., Kristunas, C., Hillier, B., Brooks, J., Fulton-Lieuw, T. & Parish, J., 1 Feb 2025, In: Journal of Infection.
Oral human papillomavirus (HPV) prevalence and genotyping among healthy adult populations in the United States and Europe: results from the PROGRESS (PRevalence of Oral hpv infection, a Global aSSessment) study
Alemany L, Felsher M, Giuliano AR, Waterboer T, Mirghani H, Mehanna H, Roberts C, Chen YT, Lara N, Lynam M, Torres M, Pedrós M, Sanchez E, Spitzer J, Sirak B, Quirós B, Carretero G, Paytubi S, Morais E, Pavón MA. Jan 2025, In: EClinicalMedicine; 79:103018. doi: 10.1016/j.eclinm.2024.103018.
NIFTy: near-infrared fluorescence (NIRF) imaging to prevent postsurgical hypoparathyroidism (PoSH) after thyroid surgery-a phase II/III pragmatic, multicentre randomised controlled trial protocol in patients undergoing a total or completion thyroidectomy
Croft J, Ainsworth G, Corrigan N, Gordon K, Perry A, Twiddy M, Strachan M, Wadsley J, Mehanna H, Sharma N, Glenister E, Stocken DD, Balasubramanian SPP. Jan 30 2025, In: BMJ Open; 15(1):e092422. doi: 10.1136/bmjopen-2024-092422.
Clinical predictive models for recurrence and survival in treated laryngeal and hypopharyngeal cancer: a systematic review and meta-analysis
Ahmad K Abou-Foul, Janine Dretzke, Esther Albon, Caroline Kristunas, David J Moore, Andreas Karwath, Georgios Gkoutos, Hisham Mehanna, Paul Nankivell; PETNECK2 Research Team, 6 Dec 2024; In: Front Oncol.
A systematic review of prognostic models for predicting recurrence and survival in patients with treated oropharyngeal cancer
Dretzke, J., Abou-Foul, A. K., Albon, E., Hillier, B., Scandrett, K., Price, M. J., Moore, D. J., Mehanna, H., Nankivell, P. & PETNECK2 Research Team, 5 Dec 2024, In: BMJ open; 14, 12, 13 p., e090393.
Fear of Cancer Recurrence and Fear of Cancer Progression, Digital Resource Engagement and Health Literacy: A Review
Mehanna, H. & Nankivell, P., 26 Nov 2024, (Accepted/In press) In: Current Oncology; 31(12):7586-7602. doi: 10.3390/curroncol31120559.
The long lost denture: a rare case of an acquired, non-malignant tracheo-oesophageal fistula
Jesani, H., Hundle, A., Nankivell, P. & Kalkat, M., 4 Nov 2024, In: Journal of Cardiothoracic Surgery; 19, 8 p., 621.
Exploring the impact of intra-tumoural heterogeneity on liquid biopsy cell-free DNA methylation and copy number in head and neck squamous cell carcinoma
Payne, K., Suriyanarayanan, H., Brooks, J., Mehanna, H., Nankivell, P. & Gendoo, D., Nov 2024, In: Oral Oncology; 158, 107011.
TNM 8 staging system beyond p16: Double HPV/p16 status is superior to p16 alone in predicting outcome in oropharyngeal squamous cell carcinoma
von Buchwald C, Jakobsen KK, Carlander AF, Tous S, Grønhøj C, Rasmussen JH, Brooks JM, Taberna M, Mena M, Morey F, Bruni L, Batis N, Brakenhoff RH, René Leemans C, Jong RJB, Klussmann JP, Wuerdemann N, Wagner S, Dalianis T, Marklund L, Mirghani H, Schache A, James JA, Huang SH, O'Sullivan B, Nankivell P, Broglie MA, Hoffmann M, Quabius ES, Anderson LA, Craig SG, Alemany L, Mehanna H; HNCIG-EPIC group. Nov 2024, In: Eur J Cancer; 211:114329. doi: 10.1016/j.ejca.2024.114329.
Evaluation of US Elastography in Thyroid Nodule Diagnosis: The ElaTION Randomized Control Trial
Mehanna, H., Sidhu, P. S., Madani, G., Woolley, R., Boelaert, K., Nankivell, P., Da Forno, P., Moreman, K., Palmer, A., Fulton-Lieuw, T., Sharma, N., Taylor, J., Rajaguru, K., Bekker, J., Vaidhyanath, R., Rehman, T. & Deeks, J., Oct 2024, In: Radiology. 313, 1, e240705.
The european organisation for research and treatment of cancer head and neck cancer module (EORTC QLQ-HN43): Estimates for minimal important difference and minimal important change.
Singer S, Hammerlid E, Tomaszewska IM, Amdal CD, Herlofson BB, Santos M, Castro Silva J, Mehanna H, Fullerton A, Young T, Fernandez Gonzalez L, Inhestern J, Pinto M, Arraras JI, Yarom N, Bonomo P, Baumann I, Galalae R, Nicolatou-Galitis O, Kiyota N, Raber-Durlacher J, Salem D, Fabian A, Boehm A, Krejovic-Trivic S, Chie WC, Taylor KJ, Sherman AC, Licitra L, Machiels JP, Bjordal K; EORTC Quality of Life Group and the EORTC Head and Neck Cancer Group., 9 Oct 2024, In: Epub. p212, 115062
Diagnostic performance of ultrasound vs. ultrasound-guided FNAc in thyroid nodules: data from the ElaTION trial.
Mehanna H, Nankivell P, Boelaert K, Woolley R, Sharma N, Sidhu PS, Madani G, Da Forno P, Moreman C, Palmer A, Fulton-Lieuw T, Taylor J, Rajaguru K, Bekker J, Vaidhyanath R, Rehman T, Deeks J., 3 Oct 2024, In: Radiology. p313, e240705
Evaluation of US Elastography in Thyroid Nodule Diagnosis: The ElaTION Randomised Control Trial.
Mehanna H, Sidhu PS, Madani G, Woolley R, Boelaert K, Nankivell P, Da Forno P, Moreman K, Palmer A, Fulton-Lieuw T, Sharma N, Taylor J, Rajaguru K, Bekker J, Vaidhyanath R, Rehman T, Deeks J. Oct 2024, In: Radiology. p313, e240705.
Digital Spatial Profiling identifies distinct patterns of immuno-oncology-related gene expression within oropharyngeal tumours in relation to HPV and p16 status
Brooks, J. M., Zheng, Y., Hunter, K., Willcox, B. E., Dunn, J., Nankivell, P., Gevaert, O. & Mehanna, H., 12 Sept 2024, In: Frontiers in Oncology. 14, 10 p., 1428741.
Real-time ultrasound elastography in the diagnosis of newly identified thyroid nodules in adults: the ElaTION RCT
Mehanna, H., Deeks, J. J., Boelaert, K., Madani, G., Sidhu, P., Nankivell, P., Sharma, N., Woolley, R., Taylor, J., Fulton-Lieuw, T. & Palmer, A., 31 Aug 2024, In: Health Technology Assessment. 28, 46, p. 1-51 51 p.
Temporal evolution and inter-patient heterogeneity in primary and recurrent head and neck squamous cell carcinoma.
Bresadola L, Weber D, Ritzel C, Löwer M, Bukur V, Akilli-Öztürk Ö, Schuster C, Gargano A, Becker J, Mehanna H, Schrörs B, Vascotto F, Sahin U, Kong A., 29 Aug 2024, In: BJC Rep
Standardised definitions and diagnostic criteria for extranodal extension detected on histopathological examination in head and neck cancer: Head and Neck Cancer International Group consensus recommendations
Abou-Foul AK, Henson C, Chernock RD, Huang SH, Lydiatt WM, McDowell L, O'Sullivan B, Perez-Ordonez B, Robinson M, Nankivell PC, Ruiz-Bravo E, Chiosea SI, Green TM, Hunter KD, Hwang JS, Koljenovic S, Koppes SA, Larsen SR, Lo AWI, Costes-Martineau V, Mittal N, Mori T, Nagao T, Panayiotides IG, Pinto CAL, Scheckenbach K, Seethala RR, Ulhøi BP, Vingiani A, Zhang Y, Yom SS, Mehanna H
Lancet Oncol. 2024 Jul;25(7):e286-e296. doi: 10.1016/S1470-2045(24)00143-8.PMID: 38936387
PET -CT-guided, symptom-based, patient-initiated surveillance versus clinical follow-up in head neck cancer patients (PETNECK2): study protocol for a multicentre feasibility study and non-inferiority, randomised, phase III trial
Nankivell P, Gaunt P, Gaunt C, Sissons J, Liaskou E, Jefferson Y, Fulton-Lieuw T, Mittal S, Mehanna H; PETNECK2 Research Team
BMC Cancer. 2024 Jul 10;24(1):823. doi: 10.1186/s12885-024-12470-9.PMID: 38987693
Criteria for the diagnosis of extra nodal extension detected on radiological imaging in head and neck cancer: HNCIG international consensus recommendations
Henson, C., Abou-Foul, A., Glastonbury, C., Huang, S. H., King, A. D., Lydiatt, W. M., McDowell, L., Nagelschneider, A. A., Nankivell, P., O'Sullivan, B., Rhys, R., Xiao, Y., Yu, E., Andrew, D., Asmussen, J. T., Bidault, F., Dankbaar, J. W., de Graaf, P., Gebrim, E. S., Hu, C., & 13 others,
Lancet Oncol. 2024 Jul;25(7):e297-e307. doi: 10.1016/S1470-2045(24)00066-4.PMID: 38936388
Clinical trial endpoint use and definitions in curative-intent trials for mucosal head and neck squamous cell carcinomas: HNCIG international consensus recommendations
Lim, A. M., McDowell, L., Hurt, C., Tourneau, C. L., Homma, A., Shenouda, G., Thompson, D. J., Moya-Plana, A., Henson, C., Szturz, P., Day, A. T., Bates, J. E., Lazarakis, S., Thariat, J., Psyrri, A., Mehanna, H. & Yom, S. S.,
Lancet Oncol. 2024 Jul;25(7):e318-e330. doi: 10.1016/S1470-2045(24)00067-6.PMID: 38936390
Assessment of endpoint definitions in recurrent and metastatic mucosal head and neck squamous cell carcinoma trials: HNCIG international consensus recommendations
Lim, A., Laskar, S., Steuer, C., Chow, V. L. Y., Szturz, P., Henson, C., Day, A. T., Bates, J. E., Lazarakis, S., McDowell, L., Mehanna, H. & Yom, S. S.,
Lancet Oncol. 2024 Jul;25(7):e308-e317. doi: 10.1016/S1470-2045(24)00068-8.PMID: 38936389
A fully automated and explainable algorithm for predicting malignant transformation in oral epithelial dysplasia.
Shephard AJ, Bashir RMS, Mahmood H, Jahanifar M, Minhas F, Raza SEA, McCombe KD, Craig SG, James J, Brooks J, Nankivell P, Mehanna H, Khurram SA, Rajpoot NM, 28 Jun 2024, In: NPJ Precis Oncol. p137.
Human papillomavirus-driven head and neck cancers in Japan during 2008-2009 and 2018-2019: The BROADEN study
Nibu KI, Oridate N, Saito Y, Roset M, Forés Maresma M, Cuadras D, Morais E, Roberts C, Chen YT, Spitzer J, Sato K, Saito I, Tazaki I, Clavero O, Schroeder L, Alemany L, Mehanna H, Mirghani H, Giuliano AR, Pavón MA, Waterboer T.
Cancer Sci. 2024 Jun 7. doi: 10.1111/cas.16230. Online ahead of print.PMID: 38847353
Advances in testing for human papillomavirus-mediated head and neck cancer
Mehanna H, Alemany L, von Buchwald C.
Curr Opin Oncol. 2024 Mar 20. doi: 10.1097/CCO.0000000000001029. Online ahead of print. PMID: 38506408
Development of the 'ACT now & check-it-out' intervention to support patient-initiated follow-up for Head and Neck cancer patients.
Matheson L, Greaves C, Duda JL, Wells M, Secher D, Rhodes P, Lorenc A, Jepson M, Ozakinci G, Watson E, Fulton-Lieuw T, Mittal S, Main B, Nankivell P, Mehanna H, Brett J; PETNECK2 research team.
Feb 2024, In: Patient Educ Couns, p119, 108033
Developing and Validating a Multivariable Prognostic-Predictive Classifier for Treatment Escalation of Oropharyngeal Squamous Cell Carcinoma: The PREDICTR-OPC Study.
Mehanna H, Rapozo D, von Zeidler SV, Harrington KJ, Winter SC, Hartley A, Nankivell P, Schache AG, Sloan P, Odell EW, Thavaraj S, Hunter KD, Shah KA, Thomas GJ, Long A, Amel-Kashipaz R, Brown RM, Conn B, Hall GL, Matthews P, Weir J, Yeo Y, Pring M, West CML, McCaul J, Golusinski P, Sitch A, Spruce R, Batis N, Bryant JL, Brooks JM, Jones TM, Buffa F, Haider S, Robinson M. 17 Jan 2024, In: Clin Cancer Res., p356 - 367
Implementing the time-to-event continual reassessment method in the presence of partial orders in a phase I head and neck cancer trial.
Patel A, Brock K, Slade D, Gaunt C, Kong A, Mehanna H, Billingham L, Gaunt P. 13 Jan 2024, In: BMC Med Res Methodol, p11
Xevinapant plus radiotherapy in resected, high-risk, cisplatin-ineligible LA SCCHN: the phase III XRay Vision study design.
Ferris RL, Mehanna H, Schoenfeld JD, Tahara M, Yom SS, Haddad R, König A, Witzler P, Bajars M, Le Tourneau C. 10 Jan 2024, In: Future Oncol, p739 -748
Results and lessons learnt from the WISTERIA phase 1 trial combining AZD1775 with cisplatin pre- or post-operatively in head and neck cancer
Kong A, Kirkham A, Savage J, Mant R, Lax S, Good J. S, Forster M, Sacco J. J, Schipani S, Harrington K, Yap C, Mehanna H.
14 Dec 2023, (Accepted/In press) In: BJC Reports.
Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation.
Wilson JA, Fouweather T, Stocken DD, Homer T, Haighton C, Rousseau N, O'Hara J, Vale L, Wilson R, Carnell S, Wilkes S, Morrison J, Ah-See K, Carrie S, Hopkins C, Howe N, Hussain M, Lindley L, MacKenzie K, McSweeney L, Mehanna H, Raine C, Whelan RS, Sullivan F, von Wilamowitz-Moellendorff A, Teare D.
Dec 2023, In: Health Technol Assess
CompARE: study protocol for a phase III randomised controlled platform trial comparing alternative regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer
Mehanna H, Gaunt P, Kong A, Hartley A, Sanghera P, Forster M, Sen M, Paleri V, Fong C, Geropantas D, Srinivasan D, Garikipati S, Moleron R, Casswell G, Aynsley E, Ward A, O'Toole L, Mirza A, Firth C, Humphreys I, & 2 others.
Dec 2023, (Accepted/In press) In: Trials.
Feasibility of mass cytometry proteomic characterisation of circulating tumour cells in head and neck squamous cell carcinoma for deep phenotyping
Payne K, Brooks J, Batis N, Khan N, El-Asrag M, Nankivell, P, Mehanna H & Taylor G.
9 Nov 2023, British Journal of Cancer. 129, 10, p. 1590-1598 9 p.
Transformer-based Model for Oral Epithelial Dysplasia Segmentation
Shephard A. J, Mahmood H, Raza S. E. A, Araujo A. L. D, Santos-Silva A. R, Lopes M. A, Vargas P. A, McCombe K, Craig S, James J, Brooks J, Nankivell P, Mehanna H, Khurram S. A. & Rajpoot N. M.
9 Nov 2023, arXiv, p. 1-5, 5 p.
Development of the ‘ACT now & check-it-out’ intervention to support patient-initiated follow up for Head and Neck cancer patients
Matheson L, Greaves C, Duda JL, Wells M, Secher D, Rhodes P, Lorenc A, Jepson M, Ozakinci G, Watson E, Fulton-Lieuw T, Mittal S, Main B, Nankivell P, Mehanna H, Brett J, and on behalf of the PETNECK2 research team.
Patient Education and Counselling. 2023
Development and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia
Mahmood H, Shephard A, Hankinson P, Bradburn M, Araujo ALD, Santos-Silva AR, Lopes MA, Vargas PA, McCombe KD, Craig SG, James J, Brooks J, Nankivell P, Mehanna H, Rajpoot N, Khurram SA.
2023. British Journal of Cancer
A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis
Schack L, Naderi E, Fachall L, Dorling L, Luccarini C, Dunning AM, Barnett G, Barrera EA, Burnet NG, Calvo LM, Diergaarde B, Dudding T, Dunning A, Duprez F, Kerns LK, Kiang MCL, Lagendijk H, Mehanna H, Ness A, Sim AYL.
2022, vol. 126, issue 7, p. 1082-1090. British Journal of Cancer
Feasibility of mass cytometry proteomic characterisation of circulating tumour cells in head and neck squamous cell carcinoma for deep phenotyping
Payne K, Brooks J, Batis N, Khan N, El-Asrag M, Nankivell P, Mehanna H, Taylor G.
2023. British Journal of Cancer
Diagnostic challenges and prognostic implications of extranodal extension in head and neck cancer: a state of the art review and gap analysis
Henson CE, Abou-foul AK, Morton DJ, McDowell L, Baliga S, Bates J, Lee A, Bonomo P, Szturz P, Nankivell P, Huang SH, Lydiatt WM, O’Sullivan B, Mehanna H.
2023, vol. 13, 2023, p. 1263347. Frontiers in oncology
A systematic review of the effectiveness of patient‐initiated follow‐up after cancer
Dretzke, J., Chaudri, T., Balaji, R., Mehanna, H., Nankivell, P., Moore, D. J. & the PETNECK2 Research Team.
21 Aug 2023, (E-pub ahead of print) In: Cancer Medicine. 15 p.
Systematic review of patients’ and healthcare professionals’ views on patient‐initiated follow‐up in treated cancer patients
Dretze J, Lorenc A, Adriano A, Herd C, Mehanna H, The PETNECK2 Research Team
16 Jun 2023, (E-pub ahead of print) In: Cancer Medicine.
Lead time to recurrence after posttreatment plasma and saliva HPV DNA testing in patients with low-risk HPV oropharynx cancer
Califano J, Yousef A, Mostafa H, Valsamakuis A, Zhang X, Batis N, Varghese C, Parish J, Forman M, Jarret J, Messer K, Mehanna H.
JAMA Otolaryngol Head Neck Surg. doi:10.1001/jamaoto.2023.1730
Published online July 27, 2023.
A Fully Automated and Explainable Algorithm for the Prediction of Malignant Transformation in Oral Epithelial Dysplasia
Shephard, A. J., Bashir, R. M. S., Mahmood, H., Jahanifar, M., Minhas, F., Raza, S. E. A., McCombe, K. D., Craig, S. G., James, J., Brooks, J., Nankivell, P., Mehanna, H., Khurram, S. A. & Rajpoot, N. M.,
Preprint 6 Jul 2023.
Oral Human Papillomavirus Prevalence and Genotyping Among a Healthy Adult Population in the US
Giuliano AR, Felsher M, Waterboer T, Mirghani H, Mehanna H, et al.
JAMA Otolaryngol Head Neck Surg. Published online August 03, 2023. doi:10.1001/jamaoto.2023.1573
Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial
Wilson, J. A., O'Hara, J., Fouweather, T., Homer, T., Stocken, D. D., Vale, L., Haighton, C., Rousseau, N., Wilson, R., McSweeney, L., Wilkes, S., Morrison, J., MacKenzie, K., Ah-See, K., Carrie, S., Hopkins, C., Howe, N., Hussain, M., Mehanna, H., Raine, C., & 3 others,
17 Jun 2023, In: The Lancet. 401, 10393, p. 2051-2059 9 p.
The role of transoral surgery in the diagnosis of carcinoma of unknown origin of the head and neck
Mehanna H
Current opinion in otolaryngology & head and neck surgery 2023, vol. 31, issue 2, 2023, p. 129-133.
10.1097/MOO.0000000000000880
Patient preference for commonly-used, head and neck cancer-specific quality of life questionnaires in the follow-up setting (Determin): A multi-centre randomised controlled trial and mixed methods study
Mehanna, H, Carter, B, Hartley, A, Abou-Foul, AK, Brooks, J, Jones, J, et al.
Clinical Otolaryngology. 2023. https://doi.org/10.1111/coa.14054
A multicenter randomized trial for quality of life evaluation by non-invasive intelligent tools during post-curative treatment follow-up for head and neck cancer: Clinical study protocol
Cavalieri S, Vener C, LeBlanc M, Lopez-Perez L, Fico G, Resteghini C, Monzani D, Marton G, Pravettoni G, Moreira-Soares M, Filippidou DE, Almeida A, Bilbao A, Mehanna H, Singer S, Thomas S, Lacerenza L, Manfuso A, Copelli C, Mercalli F, Frigessi A, Martinelli E, Licitra L; BD4QoL Consortium.
Front Oncol. 2023 Jan 31;13:1048593. doi: 10.3389/fonc.2023.1048593. eCollection 2023.PMID: 36798825
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis
Mehanna H, Taberna M, von Buchwald C, Tous S, Brooks J, Mena M, Morey F, Grønhøj C, Rasmussen JH, Garset-Zamani M, Bruni L, Batis N, Brakenhoff RH, Leemans CR, Baatenburg de Jong RJ, Klussmann JP, Wuerdemann N, Wagner S, Dalianis T, Marklund L, Mirghani H, Schache A, James JA, Huang SH, O'Sullivan B, Nankivell P, Broglie MA, Hoffmann M, Quabius ES, Alemany L; HNCIG-EPIC group.
Lancet Oncol. 2023 Feb 13:S1470-2045(23)00013-X. doi: 10.1016/S1470-2045(23)00013-X. Online ahead of print.PMID: 36796393
Practical guidance for running late-phase platform protocols for clinical trials: lessons from experienced UK clinical trials units
Love SB, Cafferty F, Snowdon C, Carty K, Savage J, Pallmann P, McParland L, Brown L, Masters L, Schiavone F, Hague D, Townsend S, Amos C, South A, Sturgeon K, Langley R, Maughan T, James N, Hall E, Kernaghan S, Bliss J, Turner N, Tutt A, Yap C, Firth C, Kong A, Mehanna H, Watts C, Hills R, Thomas I, Copland M, Bell S, Sebag-Montefiore D, Jones R, Parmar MKB, Sydes MR.
Trials. 2022 Sep 6;23(1):757. doi: 10.1186/s13063-022-06680-4.PMID: 36068599
Concordance of p16INK4a and E6*I mRNA among HPV-DNA positive oropharyngeal, laryngeal and oral cavity carcinomas from the ICO international study
Mena M, Wang X, Tous S, Quiros B, Clavero O, Alejo M, Morey F, Taberna M, Vintro XL, Rubio BL, Alos L, Mehanna H, Quint w, Pawlita M, Tommasino M, Pavon MA, Munoz N, Sanjose S, Bosch FX, Alemany L
Cancers, accepted July 2022
FBXL7 Body Hypomethylation Is Frequent in Tumors from the Digestive and Respiratory Tracts and Is Associated with Risk-Factor Exposure
Camuzi D, Buexm LA, Lourenço SQC, Grazziotin R, Guaraldi S, Valverde P, Rapozo D, Brooks JM, Mehanna H, Ribeiro Pinto LF, Soares-Lima SC.
Int J Mol Sci. 2022 Jul 15;23(14):7801. doi: 10.3390/ijms23147801. PMID: 35887149; PMCID: PMC9316635.
Characterizing the epithelial-mesenchymal transition status of circulating tumor cells in head and neck squamous cell carcinoma
Payne K, Brooks J, Batis N, Taylor G, Nankivell P, Mehanna H.
Head Neck. 2022 Aug 5. doi: 10.1002/hed.27167. Online ahead of print.PMID: 35932094
PETNECK2 Research Team. Exploring the views of patients' and their family about patient-initiated follow-up in head and neck cancer: A mixed methods study
Lorenc A, Greaves C, Duda J, Brett J, Matheson L, Fulton-Lieuw T, Secher D, Rhodes P, Ozakinci G, Nankivell P, Mehanna H, Jepson M;
Eur J Cancer Care (Engl). 2022 Jul 4:e13641. doi: 10.1111/ecc.13641. Epub ahead of print. PMID: 35789510.
Symptom-based remote assessment in post-treatment head and neck cancer surveillance: A prospective national study
Zhang H, Hardman JC, Tikka T, Nankivell P, Mehanna H, Paleri V; ENT UK, BAHNO, INTEGRATE (The UK ENT Trainee Research Network).
Clin Otolaryngol. 2022 May 30. doi: 10.1111/coa.13948. Epub ahead of print. PMID: 35634790.
An external validation of C-reactive protein reduction as a predictor of healing following laryngopharyngectomy
James T, Edwards M, Nieto H, Mehanna H, Pracy P, Jennings C, Sharma N, Nankivell P.
Clinical Otolaryngology. 2022
Prognostic stratification of HPV associated oropharyngeal cancer based on CD103+ immune cell abundance in patients treated on TROG 12.01 and De-ESCALaTE randomised trials
Rischin D, Mehanna H, Young RJ, Bressel M, Dunn J, Corry J, Soni P, Fulton-Lieuw T, Iqbal G, Kenny L, Porceddu S.
Annals of Oncology. 2022 May 4.
Clinicians' Views of Patient-initiated Follow-up in Head and Neck Cancer: a Qualitative Study to Inform the PETNECK2 Trial
Lorenc A, Wells M, Fulton-Lieuw T, Nankivell P, Mehanna H, Jepson M; PETNECK2 Research Team.
Clin Oncol (R Coll Radiol). 2022 Apr;34(4):230-240. doi: 10.1016/j.clon.2021.11.010. Epub 2021 Dec 1. PMID: 34862101; PMCID: PMC8950325.
Oral human papillomavirus (HPV) and associated factors among healthy populations: The design of the PROGRESS (PRevalence of Oral hpv infection, a Global aSSessment) study
Morais, E., Kothari, S., Roberts, C., Yen, G., Chen, Y.T., Lynam, M., Pedrós, M., Mirghani, H., Alemany, L., Pavon, M.A. and Waterboer, T., Mehanna H., 2022.
Contemporary clinical trials, 115, p.106630. 2022 Apr 1
Practical Guidance for Running Late-Phase Platform Protocols for Clinical Trials:
Love SB, Cafferty F, Snowdon C, Carty K, Savage J, Pallmann P, McParland L, Brown L, Masters L, Schiavone F, Hague D….Mehanna H.
Lessons From Experienced UK Clinical Trials Units. Submitted March 2022
Learning from COVID-19 and planning post-pandemic cities to reduce pathogen transmission pathways
Andres, L., Bryson, J. R., Mehanna, H. & Moawad, P
17 Dec 2021, (Accepted/In press) In: Town Planning Review.
The BROADEN study: The design of an observational study to assess the absolute burden of HPV-related head and neck cancers
Morais, E., Kothari, S., Chen, Y-T., Roberts, C. S., Gómez-Ulloa, D., Fenoll, R., Lara, N., Pavón, M. À., Waterboer, T., Mehanna, H., Giuliano, A. R., Mirghani, H. & Alemany, L.,
24 Nov 2021, (E-pub ahead of print) In: Contemporary Clinical Trials. p. 106631
Recurrence of papillary thyroid cancer: a systematic appraisal of risk factors
Nieto, H., Thornton, C., Brookes, K., Nobre De Menezes, A., Fletcher, A., Alshahrani, M., Kocbiyik, M., Sharma, N., Boelaert, K., Cazier, J-B., Mehanna, H., Smith, V., Read, M. & McCabe, C.,
12 Nov 2021, (Accepted/In press) In: Journal of Clinical Endocrinology and Metabolism. dgab836.
Immediate sample fixation increases Circulating Tumour Cell (CTC) capture and preserves phenotype in head and neck squamous cell carcinoma: towards a standardised approach to microfluidic CTC biomarker discovery
Payne, K., Brooks, J., Taylor, G., Batis, N., Noyvert, B., Pan, Y., Nankivell, P. & Mehanna, H.,
Cancers 3 Nov 2021; 13, 21, 5519. DOI
Development and validation of an improved classification and risk stratification system for carotid body tumors: a multinational collaborative cohort study
Mehanna, H., Mistry, P., Golusinski, P., Maio, P. D., Nankivell, P., Snider, F., Ferrante, A. M. R., Montalto, N., Nicolai, P., Marcantoni, A., Grandi, C., Zavatta, M., Grego, F., Malec, K., Hosal, S., Suslu, N., Kuscu, O., Torrealba, I., Valdes, F., Sharma, N., Ayuk, J., Monksfield, P., Irving, R., Dunn, J. A., Kay, M. & Borsetto, D.,
Head and Neck Nov 2021; 43, 11, p 3448-3458 DOI
A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma
Shaban M, Raza SE, Hassan M, Jamshed A, Mushtaq S, Loya A, Batis N, Brooks J, Nankivell P, Sharma N, Robinson M, Mehanna H, Khurram SA, Rajpoot N
Journal of Pathology, Accepted October 2021 http://doi.org/10.1002/path.5819
Clinicians' views of patient-initiated follow-up in hed and neck cancer: A qualitative study to inform the PETNECK 2 trial
Lorenc A, Wells M, Fulton-Lieuw T, Nankivell P, Mehanna H, Jepson M, on behalf of the PETNECK2 Research Team.
Accepted October 2021
Dose-Escalated Intensity Modulated Radiotherapy in Patients with Locally Advanced Laryngeal and Hypopharyngeal Cancers: ART DECO, a Phase 3 Randomised Controlled Trial
Nutting C, Griffin C, Sanghera P, Foran B, Beasley M, Bernstein D, Cosgrove V, Fisher S, West C, Sibtain A, Palaniappan N, Urbano T, Sen M, Soe W, Rizwanullah M, Wood K, Ramkumar S, Junor E, Cook A, Roques T, Scrase C, Bhide S, Gujral D, Harrington k, Mehanna H, Miah A, Emson M, Gardiner D, Morden J, Hall E on behalf of the ART DECO Trial Management Group.
European Journal of Cancer 153 (2021): 242-256.
Methodologial approach for determining the minimal important difference and minimal important change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the swallowing Scale
Singer S, Hammerlid E, Tomaszewska IM, Amdal CD, Bjordal K, Herlofson BB, Santos M, Silva J, Mehanna H, Fullerton A, Brannan C, Gonzalez LF, Inhestern J, Pinto M, Arraras JI, Yarom N, Bonomo P, Baumann I, Galalae R, Nicolatou-Talitis O.
2021 Quality of Life Research
A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma
Shaban M, Raza SE, Hasan M, Jamshed A, Mushtaq S, Loya A, Batis N, Brooks J, Nankivell P, Sharma N, Robinson M, Mehanna H, Khurram S, Rajpoot N.
arXiv preprint arXiv:2104.12862. 2021
Lack of predictive tools for conventional and targeted cancer therapy: Barriers to biomarker development and clinical translation
Batis N, Brooks J, Payne K, Sharma N, Nankivell P, Mehanna H
Advanced Drug Delivery Reviews, Accepted June 2021
Comprehensive genomic and transcriptomic analysis of three synchronous primary tumours and a recurrence from a head and neck cancer patient
Bresadola S, Weber D, Ritzel C, Löwer M, Buku V, Akilli-Öztürk Ö, Becker J, Mehanna H, Schrörs B, Vascotto F, Sahin U, Kong A.
Molecular Genetics and Genomics; Accepted July 2021
Upper aerodigestive tract squamous cell carcinomas show distinct overall DNA methylation profiles and different molecular mechanisms behind WNT signaling disruption
Coelho S, Mehanna H, Camuzi D, de Souza-Santos P, de Almeida Simão Y, Nicolau-Neto P, de Souza Almeida Lopes M, Cuenin C, Talukdar FR, Batis N, Costa I, Dias F, Esposti DD, Boroni M, Herceg Z, LF Pinto *
Cancers; Accepted June 2021
Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: a GORTEC internationally reviewed HNCIG-endorsed consensus
Thariat J, Carsuzaa F, Lapeyre M, Gregoire V, MaingonP, Beddok A, Marcy PY, Salleron J, Coutte A, Racadot S, Pointreau Y, Graff P, Beadle B, Benezery K, Biau J, Calugaru V, Casteli J, Chua M, Rito A, Dore M, Ghadjar P, Huguet F, Jardel P, Johansen J, Kimple R, Krengli M, Laskar S, McDowell L, Nichols A, Tribius S, Valduvieco I, Hu C, Liem X, Moya-Plana A, D’Onofrio I, Parvathenen U, Takier V, Orlandi E, Psyrri A, Shenouda G, Sher D, Steuer C, Sun XS, Tao Y, Thomson D, Tsai MH, Vulquin N, Grophe P, Mehanna H, Yom S, Bourhis J.
Radiotherapy and Oncology; May 2021
Differential Expression of Potential Biomarkers of Oral Squamous Cell Carcinoma Development
Pansini, P. F., do Valle, I. B., Damasceno, T. C. D., de Abreu, P. M., Có, A. C. G., López, R. V. M., Lenzi, J., Rocha, R. M., Souza, E. D., Curado, M. P., Mehanna, H., Nankivell, P., de Podestá, J. R. V. & von Zeidler, S. V.
Head and Neck Pathology, 11 Apr 2021, (E-pub ahead of print)
A Cost Utility Analysis Comparing CT Surveillance, PET-CT Surveillance, and Planned Post-Radiation Neck Dissection for Advanced Nodal HPV-Positive Oropharyngeal Cancer
Fu T, Scheffler P, Forner D, Noel C, Huang S, Gilbert R, Goldstein D, O’SullivanB, Mehanna H, Waldron J, deAlmeida J.
Cancer 1 June 2021; https://doi.org/10.1002/cncr.33653
The hidden curve behind COVID-19 outbreak: the impact of delay in treatment initiation in cancer patients and how to mitigate the additional risk of dying-the head and neck cancer model
Matos L. L, Forster C. H. Q, Marta G. N, Castro Junior G, Ridge J. A, Hirata D, Miranda-Filho A, Hosny A., Sanabria A, Gregoire V, Patel S. G, Fagan J. J, D'Cruz, A. K, Licitra, L, Mehanna H, Hao, S-P, Psyrri A, Porceddu S, Galloway T. J, Golusinski W, Lee N. Y, Shiguemori E. H, Matieli J. E, Shiguemori A. P. A. C, Diamantino L. R., Schiaveto L. F, Leão L, Castro A. F, Carvalho A. L. & Kowalski L. P.
11 Mar 2021, In: Cancer Causes & Control.
WEE1 inhibitor: clinical development
Kong A, Mehanna H
Current Oncology Reports Accepted February 2021
Safety and feasibility of surgery for oropharyngeal cancers during the SARS-CoV-2-pandemic
Gorphe P, Brandbastien B, Dietz A, Duvvuri U, Ferris R, Golusinski W, Holsinger FC, Hosal S, Lawson G, Mehanna H, Paleri V, Shaw R, Succo G, Leemans CR, Simon C
Frontiers in Oncology Accepted February 2021
Ultra-Low DNA Input into Whole Genome Methylation Assays and Detection of Oncogenic Methylation and Copy Number Variants in Circulating Tumour DNA
Whalley C, payne K, Domingo E, Blake A, Richman S, Brooks J, Batis N, Spruce R, S-cort Consortium, Mehanna H, Nankivell P, Beggs AD.
Epigenomes 2021 5(1), 6; https://doi.org/10.3390/epigenomes5010006
Human papilloma virus detection in oropharyngeal carcinomas with in situ hybridisation using hand crafted morphological features and deep central attention residual networks
Fouad S, Landini G, Robinson M, Song TH, Mehanna H
Computerized Medical Imaging and Graphics. March 2021; Volume 88. doi.org/10.1016/j.compmedimag.2021.101853
Hypofractionated chemoradiation for head and neck cancer: Data from the PET NECK trial
Vreugdenhil M, Fong C, Sanghera P, Hartley A, Dunn J, Mehanna H
Oral Oncology December 2020; https://doi.org/10.1016/j.oraloncology.2020.105112
Routine restaging after primary non-surgical treatment of laryngeal squamous cell carcinoma – a review
Seebauer CT, Hackenberg B, Grosse J, Rennert J, Jung EM, ugele I, Michaelides I, Mehanna H, Hautmann MG, Bohr C, Kunzel J.
Strahlenther Onkol. doi.org/10.1007/s00066-020-01706-9
Comparison of different guidelines for oral cancer
Kohler HF, Mehanna H, Shah JP, Sanabira A, Fagan J, Juriakose MA, Leemans R, et al
European Archives of Oto-Rhino-Laryngology and Head & Neck. DOI 10.1007/s00405-020-06423-8
The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress
Gleneadie HJ, Baker AH, Batis N, Bryant J, Jiang Y, Clokie SJH, Mehanna H, Garcia P, Gendoo DMA, Roberts S, Molinolo AA, Gutkind JS, Scheven BA, Cooper PR, Khanim FL, Wiench M
Cancer Lett. 2021 Jan 5;501:172-186. Doi: j.canlet.2020.12.029. PMID: 33359448
Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI
KreimerAR, Chaturvedi AK, Alemany L, Anantharaman D, Bray F, Carrington M, Doorbar J, D’Souza G, Fakhry C, Ferris R, Gillison M, Hayes DN, Hildesheim A, Huang SH, Kowalski LP, Lang Kuhs KA, Lewis J, Lowry D, Mehanna H, …. Brennan P
Oral Oncology. 2020 September. https://doi.org/10.1016/j.oraloncology.2020.104736
Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus
Mehanna H, Hardman JC, Shenson JA, Abou-Foul AK, Topf MC, AlFalasi M, et al.
Lancet Oncology. 2020 June 11; DOI:https://doi.org/10.1016/S1470-2045(20)30334-X
Post-Treatment Head and Neck Cancer Care: National Audit and Analysis of Current Practice in the United Kingdom in Clinical Otolaryngology
INTEGRATE (UK ENT Trainee Research Network) Ellis M, Garas G, Hardman J, Khan M, Mehanna H, Smith ME, Tikka T, Ubayasiri K,Williams R
Clinical Otolaryngology 2020; http://dx.doi.org/10.1111/coa.13616
A Cost Utility Analysis Comparing CT Surveillance, PET-CT Surveillance, and Planned Post-Radiation Neck Dissection for Advanced Nodal HPV-Positive Oropharyngeal Cancer
Fu T, Scheffler P, Forner D, Noel C, Huang S, Gilbert R, Goldstein D, O’SullivanB, Mehanna H, Waldron J, deAlmeida J.
Cancer March 2021
Differential Expression of Potential Biomarkers of Oral Squamous Cell Carcinoma Development
Pansini, P. F., do Valle, I. B., Damasceno, T. C. D., de Abreu, P. M., Có, A. C. G., López, R. V. M., Lenzi, J., Rocha, R. M., Souza, E. D., Curado, M. P., Mehanna, H., Nankivell, P., de Podestá, J. R. V. & von Zeidler, S. V.
Head and Neck Pathology, 11 Apr 2021, (E-pub ahead of print)
Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: a GORTEC internationally-reviewed HNCIG-endorsed consensus
Thariat J, Carsuzaa F, Lapeyre M, Gregoire V, MaingonP, Beddok A, Marcy PY, Salleron J, Coutte A, Racadot S, Pointreau Y, Graff P, Beadle B, Benezery K, Biau J, Calugaru V, Casteli J, Chua M, Rito A, Dore M, Ghadjar P, Huguet F, Jardel P, Johansen J, Kimple R, Krengli M, Laskar S, McDowell L, Nichols A, Tribius S, Valduvieco I, Hu C, Liem X, Moya-Plana A, D’Onofrio I, Parvathenen U, Takier V, Orlandi E, Psyrri A, Shenouda G, Sher D, Steuer C, Sun XS, Tao Y, Thomson D, Tsai MH, Vulquin N, Grophe P, Mehanna H, Yom S, Bourhis J.
Radiotherapy and Oncology; May 2021
Chaves ALF, Castro AF, Marta GN, Junior GC, Ferris RL, Giglio RE, Golusinski W, Gorphe P, Hosal S, Leemans CR, Magné N, Mehanna H, Mesía R, Netto E, Psyrri A, Sacco AG, Shah J, Simon C, Vermorken JB, Kowalski LP.
Oral Oncology June 2020.
Porceddu SV, Daniels C, Yom SS, Liu H, Waldron J, Gregoire V, Moore A, Veness M, Yao M, Johansen J, Mehanna H, Rischin D, Le QT.
Int J Radiat Oncol Biol Phys. 2020
Human Papillomavirus E6/E7 mRNA detection by in situ hybridization in oral cavity squamous cell carcinoma
Marinho de Abreu P, Bittencourt do Valle I, Damasceno TC, Gregorio Co AC, Pansini PF, Vasconcelos de Podesta JR, Duccini de Souza E, Rocha RM, Curado MP, Mehanna H, von Zeidler SV
Archives of Oral Biology. 2020 May
Rohde M, Rosenberg T, Pareek M, Nankivell P, Sharma N, Mehanna H, Godballe C.
Eur Arch Otorhinolaryngol. 2020 Jun;
Soft tissue deposit in neck dissection specimen carries a poor prognosis in oral cancer: A matched pair analysis
Malik A, Nair S, Singh A, Lamba K, Rane S, Bal M, Bhattacharjee A, Mehanna H, Chaturvedi P
Head Neck. 2020 Feb
A phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol
Kong, A., Good, J. S., Kirkham, A., Savage, J., Mant, R., Llewellyn, L., Parish, J., Spruce, R., Forster, M., Schipani, S., Harrington, K., Sacco, J. J., Murray, P., Middleton, G., Yap, C. & Mehanna, H.
BMJ open. 30 Jan 2020
Prioritisation of research topics for head and neck cancer in Africa – report of the International Collaboration On Improving Cancer outcomes in low and middle income countries – ICOnIC Africa
Mehanna, H. & Sharma, N.
Oral Oncology. 2020
Acoustofluidic Salivary Exosome Isolation: A Liquid Biopsy Compatible Approach for Human Papillomavirus-Associated Oropharyngeal Cancer Detection
Wang Z, Li F, Rufo J, Chen C, Yang S, Li L, Zhang J, Cheng J, Kim Y, Wu M, Abemayor E, Tu M, Chia D, Spruce R, Batis N, Mehanna H, Wong DTW, Huang TJ.
J Mol Diagn. 2020
Concurrent cisplatin or cetuximab with radiotherapy for HPV-positive oropharyngeal cancer: medical resource use, costs, and quality-adjusted survival from the De-ESCALaTE HPV trial
Jones, D., Mistry, P., Dalby, M., Fulton-Lieuw, T., Kong, A., Dunn, J., Mehanna, H. & Gray, A.
Jan 2020 European Journal of Cancer.
Collagen Induces a More Proliferative, Migratory and Chemoresistant Phenotype in Head and Neck Cancer via DDR1
Lai SL, Tan, ML, Hollows RJ, Robinson M, Ibrahim M, Marielewska S, Parkinson EK, Ramanthan A, Zain RB, Mehanna H, Spruce R, Wei W, Chung I, Murray P, Yap LF, Paterson IC.
Cancers 2019
Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma
Bryant, J., Batis, N., Franke, A. C., Clancey, G., Hartley, M., Ryan, G., Brooks, J., Southam, A. D., Barnes, N., Parish, J., Roberts, S., Khanim, F., Spruce, R. & Mehanna, H.
OncoTarget 27 Aug 2019
Circulating Tumour Cell Biomarkers in Head and Neck Cancer: Current Progress and Future Prospects
Payne K, Brooks J, Spruce R, Batis N, Taylor G, Nankivell P, Mehanna H.
Cancers (Basel). 2019
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC)
Cohen, E. E. W. & Mehanna, H.
J Immunother Cancer. 2019
Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer
Brooks JM, Menezes AN, Ibrahim M, Archer L, La Nl, Bagnall CJ, Zeidler SV, Valentine HR, Spruce RJ, Batis N, Bryant JL, Hartley M, Kaul N, Ryan GB, Bao R, Khattri A, Lee SL, Ogbureke KU, Middleton G, Tennant DA, Beggs AD, Deeks J, West CM, Cazier JB, Willcox BE, Seiwert TY and Mehanna H
Clin Cancer Res June 10 2019
Oropharyngeal Cancers in the East and the West - Implications of Aetiopathogenesis on Prognosis and Research
Chatterjee S, Ghosh Laskar S, Mehanna H, Nutting CM, Mallick I.
Clin Oncol (R Coll Radiol). 2019
Modelling human papillomavirus biology in oropharyngeal keratinocytes
Roberts S, Evans D, Mehanna H, Parish JL,
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2019,
Transoral tongue base mucosectomy for the identification of the primary site in the work-up of cancers of unknown origin: Systematic review and meta-analysis
Farooq S, Khandavilli S, Dretzke J, Moore D, Nakivell P, Sharma N, de Almeida J, Winter S, Simon C, Paleri V, De M, Siddiq S. Holsinger C, Ferris R, Mehanna H.
Oral Oncology. 2019;
International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ‐HN43: Phase IV
Singer S, Amdal CD, Hammerlid E, et al.
Head & Neck. 2019
Evidence for the approach to the diagnostic evaluation of squamous cell carcinoma occult primary tumors of the head and neck
Golusinski P, DiMaio P, Pehlivan B, Colley S, Nankivell P, Kong A, Hartley A, Mehanna H
Oral Oncology. Jan 2019 88
Human Papillomavirus (HPV) vaccine effectiveness and potential herd immunity for reducing oncogenic oropharyngeal HPV16 prevalence in the UK: a cross-sectional study
Mehanna, H., Bryant, T. S., Babrah, J., Louie, K., Bryant, J., Spruce, R., Batis, N., Olaleye, O., Jones, J., Struijk, L., Molijn, A., Vorsters, A., Rosillon, D., Taylor, S. & D’Souza, G.,
Clinical Infectious Diseases. 2019 Sep 2
Association between loss of Y chromosome and poor prognosis in male head and neck squamous cell carcinoma
Hollows R, Wei W, Cazier J‐B, et al.
Head Neck. 2019 Apr
Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial
Mehanna H, Robinson M, Hartley A, Kong A, Foran B, Fulton-Lieuw T, Dalby M, Mistry P, Sen M, O’Toole L, Booz H, Dyker K, Moleron R, Whitaker S, Brennan S, Cook A, Griffin M, Aynsley E, Rolles M, DeWinton E, Chan A, Srinivasan S, Grumett, J, Leemans C, Buter J, Henderson J, Harrington K, McConkey C, Gray A, Dunn J, on behalf of the De-ESCALaTE HPV Trial Group.
Lancet. 2019 Jan
Safety and Efficacy of Durvalumab With or Without Tremelimumab in Patients With PD-L1–Low/Negative Recurrent or Metastatic HNSCCThe Phase 2 CONDOR Randomized Clinical Trial
Siu LL, Even C, Mesía R, Remenar E, Daste A, Delord JP, Krauss J, Saba NF, Nabell L, Ready NE, Braña I, Kotecki N, Zandberg DP, Gilbert J, Mehanna H, Bonomi M, Jarkowski A, Melillo G, Armstrong JM, Wildsmith S, Fayette J.
JAMA Oncol. Published online November 01, 2018.
Toxicity Reduction in the Treatment of HPV Positive Oropharyngeal Cancer: Emerging Combined Modality Approaches
Deschuymer, S., H. Mehanna and S. Nuyts.
Frontiers in Oncology. 2018 8(439).
Surveillance of HPV-Positive Head and Neck Squamous Cell Carcinoma with Circulating and Salivary DNA Biomarkers
Borsetto D, Cheng J, Payne K, Nankivell P, Batis N, Rao K, Bhide S, Li F, Kim Y, Mehanna H, Wong D.
Critical Reviews in Oncogenesis. Vol 23, 2018.
The impact of institutional clinical trial recruitment versus hospital volume on survival outcomes of patients with head and neck cancer: An analysis of the PET-NECK trial outcomes, UKCRN portfolio, and Hospital Episode Statistics (HES) in England
Lin, D. J., McConkey, C. C., Nankivell, P., Dunn, J. & Mehanna, H.
1 Oct 2018 In : Oral Oncology
Surgical quality assurance in head and neck cancer trials: an EORTC Head and Neck Cancer Group position paper based on the EORTC 1420 'Best of' and 24954 'larynx preservation' study
Simon C, Caballero C, Gregoire V, Thurnher D, Koivunen P, Ceruse P, Spriano G, Nicolai P, Licitra L, Machiels JP, Hamoir M, Andry G, Mehanna H, Hunter KD, Dietz A, René Leemans C.
Eur J Cancer
PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer
Read M, Modasia B, Fletcher A, Thompson, R, Baker, K, Boelaert, K, Turnell, A, Smith, V, Mehanna, H & McCabe, C.
Cancer Research
Considerations for a head and neck smoking cessation support programme; A qualitative study of the challenges in quitting smoking after treatment for head and neck cancer
Abdelrahim, A., Balmer, C., Jones, J., Mehanna, H. & Dunn, J.
European Journal of Oncology Nursing.
Laryngeal Dysplasia and narrow band imaging: secondary analysis of published data supports the role in patient follow up
Paleri V, Sawant R, Mehanna H, Ainsworth H, and Stocken D
Clinical Otolaryngology
PO-124 PTTG and PBF functionally interact with P53 and predict overall survival in head and neck cancer
Read M, Modasia B, Fletcher A, Thompson, R, Baker, K, Boelaert, K, Turnell, A, Smith, V, Mehanna, H & McCabe, C.
ESMO Open 2018;3:
Revised Modelling of the Addition of Synchronous Chemotherapy to Radiotherapy in Squamous Cell Carcinoma of the Head and Neck—A Low α/β?
Best, J, Fong, C, Benghiat, H, Mehanna, H, Glaholm, J, & Hartley J.
Medicines 2018, 5(2), 54
Prognostic Activity of Cyclin D1 in Oral Squamous Cell Carcinoma
Valle I, Damasceno T, Pansini P, Dos W, Zolzaneli S, Camisasca D, Mehanna H, Von Zeidler S
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 2018, p179
Provision of physiotherapy rehabilitation following neck dissection in the UK
Robinson, M., Ward, L., Mehanna, H., Paleri, V. & Winter, S. C.
The Journal of laryngology and otology. 2018;1–4.
Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer
Meade, S., Gaunt, P., Hartley, A., Robinson, M., Cashmore, J., Wagstaff, L., Babrah, J., Bowden, S. J., Mehanna, H. & Sanghera, P.
Clinical Oncology. June 2018 Volume 30, Issue 6, Pages 366–374
Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams)
Grønhøj, C. , Jensen, D. H. , Dehlendorff, C. , Marklund, L. , Wagner, S. , Mehanna, H. , Munck-Wikland, E. , Ramqvist, T. , Näsman, A. , Wittekindt, C. , Würdemann, N. , Sharma, S. J. , Gattenlöhner, S. , Kiss, K. , Andersen, E. , Spruce, R. , Batis, N. , Robinson, M. , Harrington, K. , Winter, S. & 5 others
British Journal of Cancer. 24 May 118, pages1672–1681 (2018)
Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma
Payne K, Spruce R, Beggs A, Sharma N, Kong A, Martin T, Parmar S, Praveen P, Nankivell P, Mehanna H.
Basic Science Review. March 2018.
The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review
Fussey, J. M., Bryant, J. L., Batis, N., Spruce, R. J., Hartley, A., Good, J. S., McCabe, C. J., Boelaert, K., Sharma, N. & Mehanna, H
Frontiers in oncology. 30 Apr 2018 , 132
Mereotopological Correction of Segmentation Errors in Histological Imaging
Randell, D., Galton, A., Fouad, S., Mehanna, H. & Landini, G.
Journal of Imaging 12 Dec 2017, p63
Epithelium and Stroma Identification in Histopathological Images using Unsupervised and Semi-supervised Superpixel-based Segmentation
Fouad, S., Randell, D., Galton, A., Mehanna, H. & Landini, G.
Journal of Imaging. 11 Dec 2017, p61
Considerations for a head and neck smoking cessation support programme; A qualitative study of the challenges in quitting smoking after treatment for head and neck cancer
Abdelrahim, A., Balmer, C., Jones, J., Mehanna, H. & Dunn, J.
European Journal of Oncology Nursing. Volume 35, August 2018, Pages 54-611
Long-term survival outcomes in patients with surgically treated oropharyngeal cancer and defined human papilloma virus status.
Dale O.T, Sood S, Shah K.A, Han C, Rapozo D, Mehanna H, Winter, S.C.,
The Journal of Laryngology & Otology. Nov 2016, pages 1048 -1 1053
Provision of physiotherapy rehabilitation following neck dissection in the UK
Robinson, M., Ward, L., Mehanna, H., Paleri, V. & Winter, S. C.
The Journal of laryngology and otology. 2018;1–4.
Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams)
Grønhøj, C. , Jensen, D. H. , Dehlendorff, C. , Marklund, L. , Wagner, S. , Mehanna, H. , Munck-Wikland, E. , Ramqvist, T. , Näsman, A. , Wittekindt, C. , Würdemann, N. , Sharma, S. J. , Gattenlöhner, S. , Kiss, K. , Andersen, E. , Spruce, R. , Batis, N. , Robinson, M. , Harrington, K. , Winter, S. & 5 others
British Journal of Cancer. 24 May 118, pages1672–1681 (2018)
Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer
Meade, S., Gaunt, P., Hartley, A., Robinson, M., Cashmore, J., Wagstaff, L., Babrah, J., Bowden, S. J., Mehanna, H. & Sanghera, P.
Clinical Oncology. June 2018 Volume 30, Issue 6, Pages 366–374
The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review
Fussey, J. M., Bryant, J. L., Batis, N., Spruce, R. J., Hartley, A., Good, J. S., McCabe, C. J., Boelaert, K., Sharma, N. & Mehanna, H
Frontiers in oncology. 30 Apr 2018 , 132
Considerations for a head and neck smoking cessation support programme; A qualitative study of the challenges in quitting smoking after treatment for head and neck cancer
Abdelrahim, A., Balmer, C., Jones, J., Mehanna, H. & Dunn, J.
European Journal of Oncology Nursing. Volume 35, August 2018, Pages 54-611
Provision of physiotherapy rehabilitation following neck dissection in the UK
Robinson, M., Ward, L., Mehanna, H., Paleri, V. & Winter, S. C.
The Journal of laryngology and otology. 2018;1–4.
Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams)
Grønhøj, C. , Jensen, D. H. , Dehlendorff, C. , Marklund, L. , Wagner, S. , Mehanna, H. , Munck-Wikland, E. , Ramqvist, T. , Näsman, A. , Wittekindt, C. , Würdemann, N. , Sharma, S. J. , Gattenlöhner, S. , Kiss, K. , Andersen, E. , Spruce, R. , Batis, N. , Robinson, M. , Harrington, K. , Winter, S. & 5 others
British Journal of Cancer. 24 May 118, pages1672–1681 (2018)
Feasibility of Dose-escalated Hypofractionated Chemoradiation in Human Papilloma Virus-negative or Smoking-associated Oropharyngeal Cancer
Meade, S., Gaunt, P., Hartley, A., Robinson, M., Cashmore, J., Wagstaff, L., Babrah, J., Bowden, S. J., Mehanna, H. & Sanghera, P.
Clinical Oncology. June 2018 Volume 30, Issue 6, Pages 366–374
The Clinical Utility of Cell-Free DNA Measurement in Differentiated Thyroid Cancer: A Systematic Review
Fussey, J. M., Bryant, J. L., Batis, N., Spruce, R. J., Hartley, A., Good, J. S., McCabe, C. J., Boelaert, K., Sharma, N. & Mehanna, H
Frontiers in oncology. 30 Apr 2018 , 132
Circulating tumor DNA as a biomarker and liquid biopsy in head and neck squamous cell carcinoma
Payne K, Spruce R, Beggs A, Sharma N, Kong A, Martin T, Parmar S, Praveen P, Nankivell P, Mehanna H.
Basic Science Review. March 2018.
Cost-effectiveness analysis of PET-CT-guided management for locally advanced head and neck cancer
Smith, A. F., Hall, P. S., Hulme, C. T., McCabe, C. & Mehanna, H
European Journal of Cancer. November 2017, Volume 85, P. 6-14
Formation of an international intergroup to coordinate clinical trials in head and neck cancers: HNCIG
Le, Q. T., Welch, J. J., Vermorken, J. B., Rischin, D., Mehanna, H. & investigators, H. N. C. I. G. Aug 2017
Oral Oncology. 71, p. 180-18
A Q methodology study to investigate the experiences of head and neck cancer patients from diagnosis to one year
Reid, K. J., Mehanna, H. & Swift, A. 4 May 2017
European journal of cancer care
Model-based Correction of Segmentation Errors in Digitised Histological Images
Randell, D., Galton, A., Fouad, S., Mehanna, H. & Landini, G. 19 Apr 2017
Medical image understanding and analysis - MIUA 2017.
PET-NECK: a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography-computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metastases in patients with squamous cell head and neck cancer
Mehanna, H., McConkey, C. C., Rahman, J. K., Wong, W-L., Smith, A. F., Nutting, C., Hartley, A. G., Hall, P., Hulme, C., Patel, D. K., Zeidler, S. V. V., Robinson, M., Sanghera, B., Fresco, L. & Dunn, J. A. Apr 2017
Health Technology Assessment. 21, 17, p. 1-122 122 p.
Unsupervised Superpixel-based Segmentation of Histopathological Images with Consensus Clustering
Fouad, S., Randell, D., Galton, A., Mehanna, H. & Landini, G. 2017 Medical Image Understanding and Analysis: 21st Annual Conference, MIUA 2017, Edinburgh, UK, July 11-13, 2017, Proceedings. Springer, (Communications in Computer and Information Science; vol. 723)
Existing evidence on noise induced hearing loss and tinnitus in the military and other occupational groups
Evidence Synthesis Team, Institute of Applied Health Research, University of Birmingham, January 2017 ISBN No: 9780704429420
Recruitment, response rates and characteristics of 5511 people enrolled in a prospective clinical cohort study: head and neck 5000.
Ness AR, Waylen A, Hurley K, Jeffreys M, Penfold C, Pring M, Leary SD, Allmark C, Toms S, Ring S, Peters TJ, Hollingworth W, Worthington H, Nutting C, Fisher S, Rogers SN, Thomas SJ; Head and Neck 5000 Study Team.
Clin Otolaryngol. December 2016
Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin
Rachel J Watkins, Waraporn Imruetaicharoenchoke, Martin L Read, Neil Sharma, Vikki L Poole, Erica Gentillin, Sukhchain Bansal, Emy Bosseboeuf, Rachel Fletcher, Hannah R Nieto, Ujjal Mallick, Allan Hackshaw, Hisham Mehanna, Kristien Boelaert, Vicki E Smith, Christopher J McCabe.
The Journal of clinical endocrinology and metabolism. 2016, p. jc20161932
Efficacy, outcomes, and complication rates of different surgical and nonsurgical treatment modalities for recurrent/residual oropharyngeal carcinoma: A systematic review and meta-analysis
Sharan Chakkyath Jayaram, Sayed Jameel Muzaffar, Ikhlaaq Ahmed, Jagtar Dhanda, Vinidh Paleri, Hisham Mehanna.
Head & Neck 2016
HPV-related oropharyngeal cancer in the United Kingdom: an evolution in understanding of disease etiology
Andrew G Schache, Ned G Powell, Kate S Cuschieri, Max Robinson, Sam Leary, Hisham Mehanna, Davy Rapozo, Anna Long, Heather Cubie, Elizabeth Junor, Hannah Monaghan, Kevin J Harrington, Christopher M Nutting, Ulrike Schick, Andy S Lau, Nav Upile, Jon Sheard, Kath Brougham, Catharine M L West, Ken Oguejiofor & 12 others.
Cancer research 2016
ENT Trainee Research Collaborative – West Midlands. National prospective cohort study of peritonsillar abscess management and outcomes: the Multicentre Audit of Quinsies study
J Laryngol Otol. 2016 Jun 10;1–9. DOI: 10.1017/S0022215116008173 PMID: 27282632
PETCT – guided surveillance versus planned neck dissection in advanced nodal disease of head and neck cancer treated by chemoradiotherapy
Mehanna H, Wong WL, McConkey C, Rahman JK, Robinson M, Hartley AG, Nutting C, Powell N, Al-Booz H, Robinson M, Junor E, Hulme C, Smith AF, Hall P, Dunn J.
N Engl J Med. 2016 Apr 14;374(15):1444-54. doi: 10.1056/NEJMoa1514493. Epub 2016 Mar 23. PMID: 27007578
Management of advanced nodal disease in patients treated with primary chemoradiotherapy
Mehanna H, Wong WL, Dunn J.
Curr Opin Oncol. 2016 May;28(3):201-4. doi: 10.1097/CCO.0000000000000283.
HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients
Xavier Castellsague; Laia Alemany; Miquel Quer; Gordana Halec; Beatriz Quiros; Sara Tous; Omar Clavero; Llucia Alos; Thorsten Biegner; Tomasz Szafarowski; Maria Alejo; Dana Holzinger; Enrique Cadena; Edith Claros; Gillian Hall; Jan Laco; Mario Poljak; Maria Benevolo; Elena Kasamatsu; Hisham Mehanna; Cathy Ndiaye; Nuria Guimera; Belen Lloveras; Xavier Leon; Juan C. Ruiz-Cabezas; Isabel Alvarado-Cabrero; Chang-Suk Kang; Jin-Kyoung Oh; Marcial Garcia-Rojo; Ermina Iljazovic; Oluseyi F. Ajayi; Flora Duarte; Ashrafun Nessa; Leopoldo Tinoco; Marco A. Duran-Padilla; Edyta C. Pirog; Halina Viarheichyk; Hesler Morales; Valerie Costes; Ana Felix; Maria Julieta V. Germar; Marisa Mena; Arzu Ruacan; Asha Jain; Ravi Mehrotra; Marc T. Goodman; Luis Estuardo Lombardi; Annabelle Ferrera; Sani Malami; Estela I. Albanesi; Pablo Dabed; Carla Molina; Ruben Lopez-Revilla; Vaclav Mandys; Manuel E. Gonzalez; Julio Velasco; Ignacio G. Bravo; Wim Quint; Michael Pawlita; Nubia Munoz; Silvia de Sanjose; F. Xavier Bosch.
JNCI Journal of the National Cancer Institute 2016 108 (6): djv403 doi: 10.1093/jnci/djv403
Recurrent head and neck cancer: United Kingdom National Multidisciplinary deesca.
Mehanna H, Kong A, Ahmed SK.
J Laryngol Otol May 2016
Reconstructive considerations in head and neck surgical oncology: United Kingdom National Multidisciplinary Guidelines.
Ragbir M, Brown JS, Mehanna H.
J Laryngol Otol. May 2016
Oropharyngeal cancer: United Kingdom National Multidisciplinary Guidelines.
Mehanna H, Evans M, Beasley M, Chatterjee S, Dilkes M, Homer J, O'Hara J, Robinson M, Shaw R, Sloan P.
J Laryngol Otol. May 2016
The role of PET CT in the management of advanced nodal head neck cancer post chemoradiotherapy.
Wong WL, Dunn J, Mehanna H.
Transl Cancer Res. 2016
Management of neck metastases in head and neck cancer: United Kingdom National Multidisciplinary Guidelines.
Paleri V, Urbano TG, Mehanna H, Repanos C, Lancaster J, Roques T, Patel M, Sen M.
J Laryngol Otol. May 2016
Geographic variation in human papillomavirus oropharyngeal cancer: Data from 4 multi-national randomised trials
Mehanna H, Franklin N, Compton N, Robinson M, Powell N, Biswas-Baldwin N, Paleri V, Hartley A, Fresco L, Al-Booz H, Junor E, El-Hariry I, Roberts S, Harrington K, Ang K, Dunn J, Woodman C.
Head and Neck, in print 2015
Postoperative Adjuvant Lapatinib and Concurrent Chemoradiotherapy Followed by Maintenance Lapatinib Monotherapy in High-Risk Patients With Resected Squamous Cell Carcinoma of the Head and Neck: A Phase III, Randomized, Double-Blind, Placebo-Controlled Study
Harrington K, Temam S, Mehanna H, D'Cruz A, Jain M, D'Onofrio I, Manikhas G, Horvath Z, Sun Y, Dietzsch S, Dubinsky P, Holeckova P, El-Hariry I, Franklin N, Biswas-Baldwin N, Legenne P, Wissel P, Netherway T, Farrell J, Ellis C, Wang-Silvanto J, Amonkar M, Ahmed N, Santillana S, Bourhis J.
J Clin Oncol. 2015 Nov 2. pii: JCO.2015.61.4370. [Epub ahead of print]
Interventions in randomised controlled trials in surgery: issues to consider during trial design
Blencowe NS, Brown JM, Cook JA, Metcalfe C, Morton DG, Nicholl J, Sharples LD, Treweek S, Blazeby JM; Members of the MRC Hub for Trials Methodology Research Network Workshop.
Trials. 2015 Sep 4;16:392. doi: 10.1186/s13063-015-0918-4.
The 8q24 rs6983267G variant is associated with increased thyroid cancer risk
Sahasrabudhe R1, Estrada A1, Lott P1, Martin L1, Polanco Echeverry G2, Velez A1, Neta G1, Takahasi M2, Saenko V1, Mitsutake N; JTCMS Consortium, Jaeguer E1, Duque CS1, Rios A1, Bohorquez M1, Prieto R1, Criollo A1, Echeverry M1, Tomlinson I1; CORGI Consortium; TCUKIN Consortiums, Carmona LG2.
Endocr Relat Cancer. 2015 Oct;22(5):841-9. doi: 10.1530/ERC-15-0081. Epub 2015 Aug 19.
External beam radiotherapy in differentiated thyroid carcinoma: A systematic review
Fussey JM, Crunkhorn R, Tedla M, Weickert MO, Mehanna H
Head Neck. 2015 Sep 3. doi: 10.1002/hed.24218. [Epub ahead of print]
IGF-1R expression is associated with HPV-negative status and adverse survival in head and neck squamous cell cancer
Dale OT, Aleksic T, Shah KA, Han C, Mehanna H, Rapozo DC, Sheard JD, Goodyear P, Upile NS, Robinson M, Jones TM, Winter S, Macaulay VM.
Carcinogenesis. 2015 Jun;36(6):648-55. doi: 10.1093/carcin/bgv053. Epub 2015 Apr 20
Trends in head and neck cancers in England from 1995 to 2011 and projections up to 2025
Louie KS, Mehanna H, Sasieni P
Oral Oncol. 2015 Jan 22. pii: S1368-8375(15)00003-2. doi: 10.1016/j.oraloncology.2015.01.002. [Epub ahead of print]
The design of a multi-arm multi-stage (MAMS) phase III randomised controlled trial comparing alternative regimens for escalating (COMPARE) treatment of intermediate and high-risk oropharyngeal cancer with reflections on the complications of introducing a new experimental ARM
Gaunt P, Mehanna H, Yap C.
Trials. 2015; 16(suppl 2):016. DOI: 10.1186/1745-6215-16-S2-O16 PMCID: PMC4658827
Phase II, randomised, open-label study of durvalumab (MEDI14736) or tremelimumab monotherapy, or durvalumab + tremelimumab, in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): condor
Gilbert J, Le Tourneau C, Mehanna H, Fayette J, Goswami T, Emerige U, Jarkowski III A, Melillo G, and Siu L
J Immunotherapy of cancer 2015, 3(suppl 2): P152. DOI: 10.1186/2051-1426-3-S2-P152
Establishing a large prospective clinical cohort in people with head and neck cancer as a biomedical resource: head and neck 5000
Ness AR, Waylen A, Hurley K, Jeffreys M, Penfold C, Pring M, Leary S, Allmark C, Toms S, Ring S, Peters TJ, Hollingworth W, Worthington H, Nutting C, Fisher S, Rogers SN, Thomas SJ; Head and Neck 5000 Study Team
BMC Cancer. 2014 Dec 17;14:973. doi: 10.1186/1471-2407-14-973.
Resection of subsequent pulmonary metastases from treated head and neck squamous cell carcinoma; systematic review and meta-analysis
Young ER, Diakos E, Khalid-Raja M, Mehanna H.
Clin Otolaryngol. 2014 Oct 30. doi: 10.1111/coa.12348. [Epub ahead of print]
PMID: 25358605 [PubMed - as supplied by publisher]
Differences in the Recurrence and Mortality Outcomes Rates of Incidental and Nonincidental Papillary Thyroid Microcarcinoma: A Systematic Review and Meta-Analysis of 21 329 Person-Years of Follow-Up
Mehanna H, Al-Maqbili T, Carter B, Martin E, Campain N, Watkinson J, McCabe C, Boelaert K, Franklyn JA.
J Clin Endocrinol Metab. 2014 May 14:jc20132118. [Epub ahead of print]
Investigation of p16(INK4a) as a prognostic biomarker in oral epithelial dysplasia
Nankivell P, Williams H, Webster K, Pearson D, High A, MacLennan K, Senguven B, McConkey C, Rabbitts P, Mehanna H.
J Oral Pathol Med. 2014 Apr;43(4):245-9. doi: 10.1111/jop.12128. Epub 2013 Dec 26.
PMID:
24372672
[PubMed - in process]
Revised radiobiological modelling of the contribution of synchronous chemotherapy to the rate of grades 3-4 mucositis in head and neck cancer
Meade S, McConkey C, Sanghera P, Mehanna H, Hartley A.
J Med Imaging Radiat Oncol. 2013 Dec;57(6):733-8; quiz 739-40. doi: 10.1111/1754-9485.12096. Epub 2013 Jul 9.
Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia
Nankivell P, Williams H, McConkey C, Webster K, High A, MacLennan K, Senguven B, Rabbitts P, Mehanna H.
Br J Cancer. 2013 Nov 26;109(11):2864-74. doi: 10.1038/bjc.2013.600. Epub 2013 Nov 7.
LIHNCS - Lugol's iodine in head and neck cancer surgery: a multicentre, randomised controlled trial assessing the effectiveness of Lugol's iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection margins of oral and oropharyngeal squamous cell carcinoma: study protocol for a randomised controlled trial
McCaul JA, Cymerman JA, Hislop S, McConkey C, McMahon J, Mehanna H, Shaw R, Sutton DN, Dunn J.
Trials. 2013 Sep 24;14:310. doi: 10.1186/1745-6215-14-310.
Simplified bone-anchored hearing aid insertion using a linear incision without soft tissue reduction
Husseman J, Szudek J, Monksfield P, Power D, O’Leary S, Briggs R
J Laryngol Otology, 2013 Jul;127 Suppl 2:S33-8
Surgical trials in head & neck cancer - Are you serious?
Shaw R, Mehanna H.
Oral Oncol. 2013 Jun 28. doi:pii: S1368-8375(13)00609-X. 10.1016/j.oraloncology.2013.06.004. [Epub ahead of print]
Prolonged treatment with vitamin D in postmenopausal women with primary hyperparathyroidism
Rao RR, Randeva HS, Sankaranarayanan S, Narashima M, Möhlig M, Mehanna H, Weickert MO.
Endocr Connect. 2012 Jun 8;1(1):13-21. doi: 10.1530/EC-12-0008. Print 2012 Jul 1.
Oncologic outcomes of transoral laser microsurgery for radiorecurrent laryngeal carcinoma: A systematic review and meta-analysis of English-language literature
Ramakrishnan Y, Drinnan M, Kwong FN, Grant DG, Mehanna H, Jones T, Paleri V.
Head Neck. 2013 Jun 14. doi: 10.1002/hed.23291. [Epub ahead of print]
Barriers to recruitment for surgical trials in head and neck oncology: a survey of trial investigators
Kaur G, Hutchison I, Mehanna H, Williamson P, Shaw R, Tudur Smith C.
BMJ Open. 2013 Apr 11;3(4). doi:pii: e002625. 10.1136/bmjopen-2013-002625. Print 2013.
Relations between cochlear histopathology and hearing loss in experimental cochlear implantation
SJ O'Leary, P Monksfield, G Kel, T Connolly, MA Souter, A Chang, P Marovic, JS O’Leary, R Richardson, H Eastwood
Hearing Research, 2013 Apr 298: 27-35
Randomised Phase II study of oral lapatinib combined with chemoradiotherapy in patients with advanced squamous cell carcinoma of the head and neck: rationale for future randomised trials in human papilloma virus-negative disease
Harrington K, Berrier A, Robinson M, Remenar E, Housset M, de Mendoza FH, Fayette J, Mehanna H, El-Hariry I, Compton N, Franklin N, Biswas-Baldwin N, Lau M, Legenne P, Kumar R.
Eur J Cancer. 2013 May;49(7):1609-18. doi: 10.1016/j.ejca.2012.11.023. Epub 2012 Dec 19.
The binary oral dysplasia grading system: validity testing and suggested improvement
Nankivell P, Williams H, Matthews P, Suortamo S, Snead D, McConkey C, Mehanna H.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Jan;115(1):87-94. doi: 10.1016/j.oooo.2012.10.015.
Malignancy risk analysis in patients with inadequate fine needle aspiration cytology (FNAC) of the thyroid
Al Maqbali T, Tedla M, Weickert MO, Mehanna H.
PLoS One. 2012;7(11):e49078. doi: 10.1371/journal.pone.0049078. Epub 2012 Nov 19.
Salivary gland swellings
Mehanna H, McQueen A, Robinson M, Paleri V.
BMJ. 2012 Oct 23;345:e6794. doi: 10.1136/bmj.e6794. Review. No abstract available.
Prognostic biomarkers of survival in oropharyngeal squamous cell carcinoma: Systematic review and meta-analysis
Rainsbury JW, Ahmed W, Williams HK, Roberts S, Paleri V, Mehanna H.
Head Neck. 2013 Jul;35(7):1048-55. doi: 10.1002/hed.22950. Epub 2012 Sep 20.
The new Nucleus 5 model cochlear implant: a new surgical technique and early clinical results
Monksfield P, Husseman J, Cowan RSC, O’Leary SJ, Briggs RJS
Cochlear Implants International, 2012 Aug;13(3): 142-7
Validation of tissue microarrays in oral epithelial dysplasia using a novel virtual-array technique
Nankivell PC, Williams H, Bartlett JM, Mehanna H.
J Clin Pathol. 2012 Dec;65(12):1084-7. doi: 10.1136/jclinpath-2012-200974. Epub 2012 Aug 22.
Feasibility of recruitment to an oral dysplasia trial in the United Kingdom
Nankivell P, Dunn J, Langman M, Mehanna H.
Head Neck Oncol. 2012 Jun 25;4:40.
PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8
Smith VE, Read ML, Turnell AS, Sharma N, Lewy GD, Fong JC, Seed RI, Kwan P, Ryan G, Mehanna H, Chan SY, Darras VM, Boelaert K, Franklyn JA, McCabe CJ.
Endocrinology. 2012 Jul;153(7):3526-36. doi: 10.1210/en.2011-2030. Epub 2012 Apr 25.
Oropharyngeal cancer - is it time to change management according to human papilloma virus status?
Mehanna H, Olaleye O, Licitra L.
Curr Opin Otolaryngol Head Neck Surg. 2012 Apr;20(2):120-4. doi: 10.1097/MOO.0b013e3283509735.
Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24
Jones AM, Howarth KM, Martin L, Gorman M, Mihai R, Moss L, Auton A, Lemon C, Mehanna H, Mohan H, Clarke SE, Wadsley J, Macias E, Coatesworth A, Beasley M, Roques T, Martin C, Ryan P, Gerrard G, Power D, Bremmer C; TCUKIN Consortium, Tomlinson I, Carvajal-Carmona LG.
J Med Genet. 2012 Mar;49(3):158-63. doi: 10.1136/jmedgenet-2011-100586. Epub 2012 Jan 25.
Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer--systematic review and meta-analysis of trends by time and region
Mehanna H, Beech T, Nicholson T, El-Hariry I, McConkey C, Paleri V, Roberts S.
Head Neck. 2013 May;35(5):747-55. doi: 10.1002/hed.22015. Epub 2012 Jan 20.
Variation in volume definition between UK head and neck oncologists treating oropharyngeal carcinoma
Pettit L, Hartley A, Bowden SJ, Mehanna H, Glaholm J, Cashmore J, Sanghera P.
Clin Oncol (R Coll Radiol). 2011 Nov;23(9):654-5. doi: 10.1016/j.clon.2011.07.006. Epub 2011 Aug 4. No abstract available.
Dexamethasone reduces pain, vomiting and overall complications following tonsillectomy in adults: a systematic review and meta-analysis of randomised controlled trials
Diakos EA, Gallos ID, El-Shunnar S, Clarke M, Kazi R, Mehanna H.
Clin Otolaryngol. 2011 Dec;36(6):531-42. doi: 10.1111/j.1749-4486.2011.02373.x. Review.
Open conservation partial laryngectomy for laryngeal cancer: a systematic review of English langCost Effectiveness (Utility) Analysis of Bone Anchored Hearing Aids
Monksfield P, Jowett S, Reid AP and Proops DW
Otology Neurotology, 2011 Oct;32(8):1192-7
Biofilm formation on bone-anchored hearing aids
Monksfield P, Chapple ILC, Matthews JB, Grant MM, Addison O, Reid AP, Proops DW, Sammons RL
J Laryngol Otology, 2011 Nov;125(11):1125-30uage literature.
Open conservation partial laryngectomy for laryngeal cancer: a systematic review of English language literature
Thomas L, Drinnan M, Natesh B, Mehanna H, Jones T, Paleri V.
Cancer Treat Rev. 2012 May;38(3):203-11. doi: 10.1016/j.ctrv.2011.05.010. Epub 2011 Jul 20. Review.
Biomarkers in laryngeal dysplasia: a systematic review.
Nankivell P, Weller M, McConkey C, Paleri V, Mehanna H.
Head Neck. 2011 Aug;33(8):1170-6. doi: 10.1002/hed.21592. Epub 2010 Nov 17. Review.
Re-feeding syndrome in head and neck--prevention and management
Ahmed S, Travis J, Mehanna H.
Oral Oncol. 2011 Sep;47(9):792-6. doi: 10.1016/j.oraloncology.2010.06.009. Epub 2011 Jul 5. Review.
Head and neck cancer-part 1: epidemiology, presentation, and preservation
Mehanna H, Paleri V, West CM, Nutting C.
Clin Otolaryngol. 2011 Feb;36(1):65-8. doi: 10.1111/j.1749-4486.2010.02231.x. Review. No abstract available.
Oncologic outcomes of open conservation laryngectomy for radiorecurrent laryngeal carcinoma: a systematic review and meta-analysis of English-language literature
Paleri V, Thomas L, Basavaiah N, Drinnan M, Mehanna H, Jones T.
Cancer. 2011 Jun 15;117(12):2668-76. doi: 10.1002/cncr.25831. Epub 2011 Feb 1.
Review.Oral dysplasia: biomarkers, treatment, and follow-up
Nankivell P, Mehanna H.
Curr Oncol Rep. 2011 Apr;13(2):145-52. doi: 10.1007/s11912-010-0150-z.
The risk and interval to malignancy of patients with laryngeal dysplasia; a systematic review of case series and meta-analysis
Weller MD, Nankivell PC, McConkey C, Paleri V, Mehanna HM.
Clin Otolaryngol. 2010 Oct;35(5):364-72. doi: 10.1111/j.1749-4486.2010.02181.x. Review.
Who should be offered sperm banking for fertility preservation? A survey of UK oncologists and haematologists
Gilbert E, Adams A, Mehanna H, Harrison B, Hartshorne GM.
Ann Oncol. 2011 May;22(5):1209-14. doi: 10.1093/annonc/mdq579. Epub 2010 Oct 27.
Head and neck cancer--Part 2: Treatment and prognostic factors
Mehanna H, West CM, Nutting C, Paleri V.
BMJ. 2010 Sep 28;341:c4690. doi: 10.1136/bmj.c4690. Review.
Hypofractionated accelerated radiotherapy with concurrent carboplatin for locally advanced squamous cell carcinoma of the head and neck
Chan AK, Sanghera P, Choo BA, McConkey C, Mehanna H, Parmar S, Pracy P, Glaholm J, Hartley A.
Clin Oncol (R Coll Radiol). 2011 Feb;23(1):34-9. doi: 10.1016/j.clon.2010.07.015. Epub 2010 Sep 21.
Head and neck cancer--Part 1: Epidemiology, presentation, and prevention
Mehanna H, Paleri V, West CM, Nutting C.
BMJ. 2010 Sep 20;341:c4684. doi: 10.1136/bmj.c4684. Review.
Correlation of currently used radiobiological parameters with local control and acute and late mucosal toxicity in randomised studies of altered fractionation for locally advanced head and neck cancer
Hartley A, Sanghera P, Kazi W, Mehanna H, McConkey C, Glaholm J, Fowler J.
Clin Oncol (R Coll Radiol). 2011 Feb;23(1):29-33. doi: 10.1016/j.clon.2010.08.007. Epub 2010 Sep 9.
TNM classification of malignant tumours 7th edition: what's new for head and neck?
Paleri V, Mehanna H, Wight RG.
Clin Otolaryngol. 2010 Aug;35(4):270-2. DOI: 10.1111/j.1749-4486.2010.02141.x. PMID: 20738334
Consensus statement by otorhinolaryngologists and pathologists on the diagnosis and management of laryngeal dysplasia.
Mehanna H, Paleri V, Robson A, Wight R, Helliwell T.
Clin Otolaryngol. 2010 Jun;35(3):170-6. DOI: 10.1111/j.1749-4486.2010.02119.x. PMID: 20636735
Quality-of-life considerations in treatment of unresectable, recurrent head and neck cancer.
McLarnon C, Kulloo P, Mehanna H, Kelly C, Paleri V.
Expert Rev Anticancer Ther. 2010 Mar;10(3):345-52. DOI: 10.1586/era.10.13. PMID: 20214516
Postoperative hypocalcemia-The difference a definition makes.
Mehanna HM, Jain A, Randeva H, Watkinson J, Shaha A.
Head Neck. 2010 Mar;32(3):279-83. DOI: 10.1002/hed.21175. PMID: 19691027
Oropharygeal carcinoma related to human papillomavirus (editorial).
Mehanna H, Jones TM, Gregoire V, Ang KK.
BMJ, 2010 Mar 25;340:c1439. DOI: 10.1136/bmj.c1439. PMID: 20339160
Treatment and follow-up of oral dysplasia – a systematic review and meta-analysis.
Mehanna HM, Rattay T, Smith J, McConkey CC.
Head Neck. 2009 Dec;31(12):1600-9. DOI: 10.1002/hed.21131. PMID: 19455705
Radiobiological Modelling of the Therapeutic Ratio for the Addition of Synchronous Chemotherapy to Radiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck.
Hartley A, Sanghera P, Glaholm J, Mehanna H, McConkey C, Fowler J.
Clin Oncol (R Coll Radiol). 2010 Mar;22(2):125-30. DOI: 10.1016/j.clon.2009.10.004. PMID: 19880297
ENT-UK Head and Neck Group. Management of laryngeal dysplasia in the United Kingdom: a web-based questionnaire survey of current practice.
Paleri V, Mackenzie K, Wight RG, Mehanna H, Pracy P, Bradley PJ.
Clin Otolaryngol. 2009 Aug;34(4):385-9. DOI: 10.1111/j.1749-4486.2009.01938.x PMID: 19673992
Biomarkers in dysplasia of the oral cavity: A systematic review.
Smith J, Rattay T, McConkey C, Helliwell T, Mehanna H.
Oral Oncol. 2009 Aug;45(8):647-53. DOI: 10.1016/j.oraloncology.2009.02.006. PMID: 19442563
The risk and interval to malignancy of patients with laryngeal dysplasia; a systematic review of case series and meta-analysis.
WellerMD, Nankivell PC, McConkey CC, Paleri V, Mehanna H.
Clin Otolaryngol. 2010 Oct;35(5):364-72. DOI: 10.1111/j.1749-4486.2010.02181.x. PMID: 21108746
A second national survey of health-related quality of life questionnaires in head and neck oncology.
Kanatas AN, Mehanna HM, Lowe D, Rogers SN.
Ann R Coll Surg Engl. 2009 Jul; 91(5): 420–425. DOI: 10.1308/003588409X428306 PMID: 19409153
Investigating the thyroid nodule.
Mehanna HM, Jain A, Morton RP, Watkinson J, Shaha A.
BMJ. 2009 Mar 13;338:b733. DOI: 10.1136/bmj.b733. PMID: 19286747
Refeeding syndrome - awareness, prevention and management.
Mehanna H, Nankivell PC, Moledina J, Travis J.
Head Neck Oncol. 2009 Jan 26;1(1):4. DOI: 10.1186/1758-3284-1-4. PMID: 19284691
Advanced head and neck cancer: is there a role for fluorodeoxyglucose PET/computed tomography?
Wong WL, Nutting C, Dunn J, Fisher S, MacLennan K, MacCabe C, Mehanna H.
Nucl Med Commun. 2009 Jan;30(1):2-4. DOI: 10.1097/MNM.0b013e32831a9aac PMID: 19306509
Setting up a minimally invasive, endoscopically assisted parathyroidectomy service in the UK on a shoe-string: how we do it.
Mehanna HM, Abdelrahim A, Sankar S, Randeva H, Lehnert H.
Clin Otolaryngol. 2008 Oct;33(5):491-4. DOI: 10.1111/j.1749-4486.2008.01793.x PMID: 18983389
Refeeding syndrome: what it is, and how to prevent and treat it.
Mehanna HM, Moledina J, Travis J.
BMJ. 2008 Jun 28;336(7659):1495-8. DOI: 10.1136/bmj.a301 PMID: 18583681
A systematic review and meta-analysis of the role of positron emission tomography in the follow-up of head and neck squamous cell carcinoma following radiotherapy or chemoradiotherapy.
Isles MG, McConkey C, Mehanna HM.
Clin Otolaryngol. 2008 Jun;33(3):210-22. DOI: 10.1111/j.1749-4486.2008.01688.x. PMID: 18559026 PMID: 18559026
The association of psychosocial factors and survival in head and neck cancer.
Mehanna HM, De Boer MF, Morton RP.
Clin Otolaryngol. 2008 Apr;33(2):83-9. DOI: 10.1111/j.1749-4486.2008.01666.x PMID: 18429854
Multidisciplinary team meetings –what, where, when, and why?
Rattay, T, Mehanna HM.
Student BMJ, April 2008.
Will measuring quality of life in head and neck cancer alter individuals' treatment?
Mehanna HM.
Curr Opin Otolaryngol Head Neck Surg. 2007 Apr;15(2):57-62. DOI: 10.1097/MOO.0b013e3280803d86 PMID: 17413403
Prediction of pharyngocutaneous fistulas after laryngectomy.
Morton RP, Mehanna H, Hall FT, McIvor NP.
Otolaryngol Head Neck Surg. 2007 Apr;136(4 Suppl):S46-9. DOI: 10.1016/j.otohns.2006.11.030 PMID: 17398341
Facial palsy as the presenting complaint of perineural spread from cutaneous squamous cell carcinoma of the head and neck.
Mehanna HM, John S, Morton RP, Chaplin JM, McIvor NP.
ANZ J Surg. 2007 Mar;77(3):191-3. DOI: 10.1111/j.1445-2197.2006.04007.x PMID: 17306001
Patients' views on the utility of quality of life questionnaires in head and neck cancer: a randomised trial.
Mehanna HM, Morton RP.
Clin Otolaryngol. 2006 Aug;31(4):310-6. DOI: 10.1111/j.1749-4486.2006.01256.x PMID: 16911650
Deterioration in quality-of-life of late (10-year) survivors of head and neck cancer.
Mehanna HM, Morton RP.
Clin Otolaryngol. 2006 Jun;31(3):204-11. DOI: 10.1111/j.1749-4486.2006.01188.x PMID: 16759240
Why are head and neck cancer clinicians not measuring quality of life?
Mehanna HM, Morton RP.
J Laryngol Otol. 2006 Oct;120(10):861-4. DOI: 10.1017/S0022215106001411 Epub 2006 May 17. PMID: 16707035
Does quality of life predict long-term survival in patients with head and neck cancer?
Mehanna HM, Morton RP.
Arch Otolaryngol Head Neck Surg. 2006 Jan;132(1):27-31. DOI: 10.1001/archotol.132.1.27 PMID: 16707035
Suspending tonsillectomy: the effects on primary and secondary acute care in Scotland.
Mehanna H, Rejali D, Murray A.
Scott Med J. 2004 Nov;49(4):144-5. doi: 10.1177/003693300404900409. PMID: 15648709
Fungal laryngitis in immunocompetent patients.
Mehanna HM, Kuo T, Chaplin J, Taylor G, Morton RP.
J Laryngol Otol. 2004 May;118(5):379-81. DOI: 10.1258/002221504323086615 PMID: 15165317
Growth rate of non-vestibular intracranial schwannomas.
O'Reilly BF, Mehanna H, Kishore A, Crowther JA.
Clin Otolaryngol Allied Sci. 2004 Feb;29(1):94-7. DOI: 10.1111/j.1365-2273.2004.00770.x PMID: 14961859
Benefit from endoscopic sinus surgery.
Mehanna H, Mills J, Kelly B, McGarry GW.
Clin Otolaryngol Allied Sci. 2002 Dec;27(6):464-71. DOI: 10.1046/j.1365-2273.2002.00610.x PMID: 12472513
Benefit from adult day case tonsillectomy – is it comparable to in-patient tonsillectomy?
Mehanna HM, Kelly B, Browning GG.
J One Day Surg, Vol 12 (2) Autumn 2002. ISSN No. 0963-5386
National audit of the management of peritonsillar abscess.
Mehanna HM, Al-Bahnasawi L, White A.
Postgrad Med J. 2002 Sep;78(923):545-8. DOI:10.1136/pmj.78.923.545 PMID: 12357017
Early discharge following nasal pack removal: is it feasible?
Mehanna H, Abdelkader M, Albahnasawy L, Johnston A.
Clin Otolaryngol Allied Sci. 2002 Jun;27(3):153-5. PMID: 12071987
Adult daycase tonsillectomy – a prospective pilot.
Mehanna HM, Hattie K, McLintock TTC, MacKenzie K.
J One Day Surg 2001, 11(1) Summer 01, 10-12 ISSN No. 0963-5386
Ductal carcinoma in situ of the breast -- among factors predicting for recurrence, distance from the nipple is important.
Stallard S, Hole DA, Purushotham AD, Hiew LY, Mehanna H, Cordiner C, Dobson H, Mallon EA, George WD
Eur J Surg Oncol. 2001 Jun;27(4):373-7. DOI: 10.1053/ejso.2001.1123 PMID: 11417983
The case of the missing carotid artery - a well aimed knife!
Mehanna HM, MacGregor FB.
J Laryngol Otol. 1998 Apr;112(4):387-8. PMID: 9659506
