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The Efficacy and Cost effectiveness of Real Time Ultrasound Elastography in The Investigation Of Thyroid Nodules and the diagnosis of thyroid cancer

Acronym:  ElaTION

ElaTION trial is a Randomised controlled trial comparing Real time Ultrasound Elastography (RTE) against standard practice of Ultrasound for the investigation of Thyroid Nodules and diagnosis of thyroid cancer. 


Inclusion criteria

1. Patients with single or multiple thyroid nodules whether solid, cystic or mixed, undergoing investigation who have not undergone previous FNAC.

2. Aged 18 or over

3. Patient able and willing to give written informed consent.

Exclusion Criteria

1. Patients who have undergone previous thyroid FNAC

2. Patients with a bleeding diathesis that precludes FNAC.

3. Patients with a needle phobia.

4. Pregnant patients

5. Patients with purely cystic nodules or with recent haemorrhage, with no solid component

Currently in set up

Lead Centre:
Birmingham Clinical Trials Unit (BCTU), The University of Birmingham

Study Coordinator:
Rebecca Howard
Birmingham Clinical Trials Unit (BCTU)
School of Health & Population Sciences
College of Medical and Dental Sciences
Public Health Building
University of Birmingham
B15 2TT

Tel:           0121 4142779
Fax:           0121 415 8871


Study Website:

Charity appeal

Find out more about our £1m Charity appeal for the AcceleraTED cancer Treatment programme.